NCT06263517 - Clinical Trial to Assess Efficacy, Tolerability of Rising Doses of Clodronate in Painful Knee Osteoarthritis Patients | Biotech Hunter

Enrollment

296

Participants

Timeline

Start Date

October 12, 2023

Primary Completion Date

July 31, 2025

Study Completion Date

October 31, 2025

Conditions

Osteoarthritis of Knee

Interventions

DRUG

Clodronate

For Arm 1, patients will be treated with intra articular clodronate 2 mg/2 ml from Baseline to Week 3

DRUG

Clodronate

For Arm 2, patients will be treated with intra articular clodronate 5 mg/2 ml from Baseline to Week 3

DRUG

Clodronate

For Arm 3, patients will be treated with intra articular clodronate 10 mg/2 ml from Baseline to Week 3

DRUG

Placebo

For Arm 4, patients will be treated with Placebo 2 ml from Baseline to Week 3

Trial Locations (11)

10043

NOT_YET_RECRUITING

Azienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano

15122

RECRUITING

Centro Riabilitativo Polifunzionale Teresio Borsalino, Alessandria

16132

RECRUITING

IRCCS Ospedale Policlinico San Martino, Genova

17100

NOT_YET_RECRUITING

Ospedale San Paolo, Savona

37134

RECRUITING

"Ospedale Policlinico G.B. Rossi Borgo Roma", Verona

46042

RECRUITING

IRCCS Istituti Clinici Maugeri, Castel Goffredo

46043

RECRUITING

Ospedale San Pellegrino, Castiglione delle Stiviere

46049

RECRUITING

Ospedale Civile Servizio di Riabilitazione Funzionale, Volta Mantovana

53100

RECRUITING

Azienda Ospedaliero Universitaria Senese, Siena

00148

RECRUITING

Ospedale Israelitico, Roma

00189

RECRUITING

Ospedale San Pietro, Rome