Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis

PHASE2RecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

February 1, 2026

Study Completion Date

February 28, 2026

Conditions
Osteo Arthritis KneeArthritis
Interventions
DEVICE

Sustained Acoustic Device with 2.5% Diclofenac Patch

Patients apply the SAM Ultrasonic Diathermy Device daily for 1-4 hours of continuous therapeutic ultrasound at 3 megahertz(MHz) frequency and 0.132 Watts/cm\^2 with 2.5% Diclofenac patches.

DEVICE

Sustained Acoustic Device with 0% Diclofenac Patch

Patients apply the SAM Ultrasonic Diathermy Device daily for 1-4 hours with 0% diclofenac patches.

DRUG

2.5% Diclofenac Patches

Topical pain relief-gel worn for 4 hours at least 5 days a week via SAM patch.

OTHER

SAM Patch

Ultrasound gel without additional pain relief medication worn for 4 hours at least 5 days a week via SAM patch.

Trial Locations (3)

13053

RECRUITING

Cayuga Medical Center - Medical Pain Consultants, Dryden

06905

RECRUITING

Orthopaedic Foundation, Stamford

06611

RECRUITING

ZetrOZ Systems, Trumbull

All Listed Sponsors
lead

ZetrOZ, Inc.

INDUSTRY

NCT06257537 - Sustained Acoustic Medicine for Symptomatic Treatment of Knee Pain Related to Osteoarthritis | Biotech Hunter | Biotech Hunter