"The Maintenance Treatment of ITIVA in AML Patients"

NARecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

July 11, 2023

Primary Completion Date

March 1, 2025

Study Completion Date

May 1, 2027

Conditions
Acute Myeloid LeukemiaMaintenance TreatmentMinor Residue DiseaseInterferon-α-1bInterleukin-2ThalidomideVenentoclaxAzacitidine
Interventions
DRUG

recombinant human interference'- α- 1b, interleukin-2, thalidomide, Venentoclax and Azacitidine

"Patients in arm1 were randomly divided into two groups, namely the interference'- α- 1b, interleukin-2, thalidomide treatment group and the VA treatment group. After receiving a two cycle protocol, patients were evaluated for the endpoint of the trial and their MRD conversion rate was calculated.~Patients in arm2 will receive triple maintenance treatment, completing three alternative regimens into one cycle. The regimen maintenance treatment will be maintained for a total of 8 cycles. Each medication regimen takes 28 days as a cycle. The number of days administered per cycle can be adjusted based on the patient's blood count."

Trial Locations (1)

450000

RECRUITING

The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou

All Listed Sponsors
lead

Henan Cancer Hospital

OTHER_GOV