360
Participants
Start Date
March 1, 2022
Primary Completion Date
February 28, 2030
Study Completion Date
February 28, 2030
Food allergy desensitization / Oral Immunotherapy
"Participants consume increasing doses of allergenic food daily until they reach a maintenance dose. In the case of the High Dose Arm, participants will progress to a daily dose of either 1200 mg, 300 mg or 200 ml of egg, peanut or milk respectively.~Participants randomized to the Low Dose Arm also begin by consuming small amounts of the allergenic food, gradually increasing the daily dose. However, participants in this group only progress to 300 ml, 30 mg or 50 ml daily dose of egg, peanut or milk respectively.~The Cooked/Transformed Allergen Arm begins the desensitization with a cooked or transformed form of the allergen - muffins in the case of egg or milk, Bamba puffs in the case of peanut. Participants take increasing amounts of these products (one muffin for egg and milk and four Bamba puffs for peanut) then transition to egg, milk or peanut. Participants then continue their dose progression, getting to 1200 mg, 200 ml or 300 mg for egg, milk and peanut respectively."
RECRUITING
Research Institute of the McGill University Health Centre, Montreal
The Hospital for Sick Children
OTHER
McGill University Health Centre/Research Institute of the McGill University Health Centre
OTHER