Phase 1 Study for IPG11406 in Health Volunteer

PHASE1RecruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

February 24, 2024

Primary Completion Date

February 28, 2025

Study Completion Date

April 30, 2025

Conditions
Inflammatory Bowel Diseases
Interventions
DRUG

IPG11406

"IPG11406 Activity: An antagonist of the GPR183 Dosage form: Tablet Strength: 0.5 mg, 10 mg and 40 mg Storage:15 \~ 25 °C in a tightly sealed container, protect from light Administration: In each cohort, IPG11406 or placebo tablets are orally administered once on Day 1 (Part A) or daily for 10 days from Day 1 to Day 10 (Part B) in a fasted state. Oral doses will be administered with 240 ml of water. Tablets should not be chewed or crushed.~Participants in the FE Cohort will receive a second single dose of IPG11406 following a standardized high fat meal upon ≥4 days washout period after the first dose.~IPG11406 Placebo Placebo tablets: tablets identical to IPG11406 tablets"

Trial Locations (1)

310013

RECRUITING

Zhejiang Hospital, Hangzhou

All Listed Sponsors
collaborator

Zhejiang Hospital

OTHER

lead

Nanjing Immunophage Biotech Co., Ltd

INDUSTRY