Shortened Regimen for Drug-susceptible TB in Children

PHASE3RecruitingINTERVENTIONAL
Enrollment

860

Participants

Timeline

Start Date

January 15, 2025

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2027

Conditions
TuberculosisTuberculosis, PulmonaryTuberculosis, Lymph NodeMycobacterium Tuberculosis
Interventions
DRUG

Isoniazid

Once daily weight-based dose

DRUG

Rifampin

Once daily weight-based dose

DRUG

Pyrazinamide

Once daily weight-based dose

DRUG

Ethambutol

Once daily weight-based dose

DRUG

Rifapentine

Once daily weight-based dose

DRUG

Moxifloxacin

Once daily weight-based dose

Trial Locations (9)

Unknown

NOT_YET_RECRUITING

Indian Council of Medical Research - National Institute for Research in Tuberculosis, Chennai

NOT_YET_RECRUITING

Dr. D.Y. Patil Medical College, Hospital and Research Center, Pune

NOT_YET_RECRUITING

Faculty of Medicine, Universitas Padjadjaran, Bandung

NOT_YET_RECRUITING

Instituto Nacional de Saúde (INS), Maputo

NOT_YET_RECRUITING

Africa Health Research Institute (AHRI), Durban

RECRUITING

MU-JHU Care Ltd, Kampala

RECRUITING

University of Zambia, School of Medicine, Lusaka

NOT_YET_RECRUITING

Arthur Davison Children's Hospital, Ndola

NOT_YET_RECRUITING

Harare Health and Research Consortium (HHRC), Harare

All Listed Sponsors
collaborator

United States Agency for International Development (USAID)

FED

lead

Johns Hopkins University

OTHER