ICVAX as a HIV Therapeutic DNA Vaccine

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

February 14, 2023

Primary Completion Date

September 30, 2024

Study Completion Date

June 30, 2025

Conditions
Human Immunodeficiency VirusHuman Immunodeficiency Virus I Infection
Interventions
BIOLOGICAL

ICVAX

ICVAX is a HIV therapeutic DNA drug developed by Immuno Cure Group based on the PD-1-Enhanced DNA Vaccine Technology platform. The unit dose strength is 2 mg in 1 mL. The dose volume is 0.5 mL/dose for the Low-dose Group, 1.0 mL/dose for the Medium-dose Group, and 2.0 mL/dose for the High-dose Group.

OTHER

Placebo

Phosphate buffered saline of the same volume will be administered. The dose volume is 0.5 mL/dose for the Low-dose Group, 1.0 mL/dose for the Medium-dose Group, and 2.0 mL/dose for the High-dose Group.

Trial Locations (1)

518112

Shenzhen Third People's Hospital, Shenzhen

All Listed Sponsors
collaborator

Shenzhen Third People's Hospital

OTHER

collaborator

Shenzhen Immuno Cure Biomedical Company Limited

INDUSTRY

lead

Immuno Cure Holding (HK) Limited

INDUSTRY