Evaluation of Rapid First-line Genome Sequencing for Prenatal Diagnosis of Congenital Malformations in Comparison With Chromosomal Microarray and Exome Sequencing

RecruitingOBSERVATIONAL
Enrollment

180

Participants

Timeline

Start Date

March 27, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Congenital Malformation
Interventions
BIOLOGICAL

foetal amniotic fluid sample

At the inclusion visit, during the foetal samples taken for the CMA/ES as part of the care.

BIOLOGICAL

blood samples

2 x 5ml blood EDTA tubes for both parents

OTHER

semi-structured online interviews

25 included couples will be invited to take part in 2 semi-structured online interviews (by telephone or videoconference)

Trial Locations (1)

21000

RECRUITING

Chu Dijon Bourgogne, Dijon

All Listed Sponsors
lead

Centre Hospitalier Universitaire Dijon

OTHER