15
Participants
Start Date
December 19, 2024
Primary Completion Date
December 11, 2026
Study Completion Date
December 11, 2026
CMV/HIV-CAR T Cells
Eligible participants will temporarily interrupt their ART regimen for 4 days prior to leukapheresis to prevent residual cell drug levels that could inhibit lentiviral transduction of the T cells during CAR T cewll manufacturing. Participants will resume their ART regimen immediately after leukapheresis. Once the final cell product is released, participants will receive a single intravenous (IV)infusion of autologous CMV/HIV-CAT T cells (defined as Day 0). Up to three doses of CMV/HIV-CAR T cewlls may be explored.
RECRUITING
City of Hope Medical Center, Duarte
RECRUITING
UCSD, Division of Infectious Diseases and Global Public Health, San Diego
City of Hope Medical Center
OTHER