Efficacy and Safety of Combination Therapy With Bojungikki-tang and Pembrolizumab Monotherapy in Patients With Advanced Non-small Cell Lung Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

February 8, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Non-small Cell Lung Cancer
Interventions
DRUG

Bojungikki-tang(BJIKT)

"Bojungikgitang, which is a classical formulation widely used in South Korea, China, and Japan for a long time, has been reported to have following anticancer activities.~1. Protective effect of intestine and hematopoietic organs against radiation damage~2. Improving localized radiotherapy-induced immune deterioration~3. Improving cancer-related fatigue and QOL~4. Reducing radiation or chemotherapy induced side effects"

DRUG

Pembrolizumab

It is a humanized antibody used in cancer immunotherapy for various types of cancer, including lung cancer. It targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes. It was approved for medical use in the U.S. in 2014.

Trial Locations (7)

14068

RECRUITING

Hallym University Medical Center, Anyang-si

50612

RECRUITING

Pusan National University Yangsan Hospital, Yangsan

02447

RECRUITING

Kyung Hee University Hospital, Seoul

04763

RECRUITING

Hanyang University Seoul Hospital, Seoul

06351

RECRUITING

Samsung medical center, Seoul

08308

RECRUITING

Korea University Guro Hospital, Seoul

Unknown

RECRUITING

The catholic university of Korea Seoul Saint. Mary's hospital, Seoul

All Listed Sponsors
lead

Korea Institute of Oriental Medicine

OTHER_GOV