36
Participants
Start Date
February 4, 2025
Primary Completion Date
June 30, 2026
Study Completion Date
June 30, 2026
Biospecimen Collection
Undergo blood and CSF sample collection
Bone Marrow Aspiration
Undergo bone marrow biopsy and aspiration
Bone Marrow Biopsy
Undergo bone marrow biopsy and aspiration
Cytarabine
Given IV and IT
Echocardiography Test
Undergo ECHO
Fludarabine
Given IV
Hydrocortisone Sodium Succinate
Given IT
Imetelstat
Given IV
Leucovorin Calcium
Given IV or PO
Lumbar Puncture
Undergo lumbar puncture
Methotrexate
Given IT
RECRUITING
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
RECRUITING
Children's Hospital of Pittsburgh of UPMC, Pittsburgh
RECRUITING
Children's Hospital of Philadelphia, Philadelphia
RECRUITING
Children's National Medical Center, Washington D.C.
RECRUITING
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta
SUSPENDED
Children's Hospital of Alabama, Birmingham
RECRUITING
Saint Jude Children's Research Hospital, Memphis
RECRUITING
Cincinnati Children's Hospital Medical Center, Cincinnati
RECRUITING
Riley Hospital for Children, Indianapolis
RECRUITING
C S Mott Children's Hospital, Ann Arbor
RECRUITING
University of Minnesota/Masonic Cancer Center, Minneapolis
RECRUITING
Lurie Children's Hospital-Chicago, Chicago
RECRUITING
Washington University School of Medicine, St Louis
RECRUITING
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
RECRUITING
Children's Hospital Colorado, Aurora
RECRUITING
Children's Hospital of Orange County, Orange
RECRUITING
UCSF Medical Center-Mission Bay, San Francisco
Collaborators (1)
Geron Corporation
INDUSTRY
National Cancer Institute (NCI)
NIH
Children's Oncology Group
NETWORK