A Study of Continued Treatment With Regorafenib in Participants With Solid Tumors Who Have Participated in Other Bayer Studies

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

January 24, 2024

Primary Completion Date

April 27, 2028

Study Completion Date

April 27, 2028

Conditions
Solid Malignant Tumors
Interventions
DRUG

Regorafenib (Stivarga, BAY73-4506)

Participants will be treated with the regorafenib dose taken during the last cycle of the feeder study. Adult participants will receive either 60, 80, 90, 120, or 160 mg orally (p.o.) once daily (qd) for 3 weeks of every 4-week cycle (i.e. 3 weeks on, 1 week off). Pediatric participants will receive 82 mg/m\^2 p.o. qd for 14 days, in a 14 days on/7 days off schedule (21-day cycle).

Trial Locations (7)

3080

Seoul National University Hospital, Seoul

28009

Hospital Infantil Universitario Nino Jesus - Oncologia Pediatrica, Madrid

59037

Hopital Claude Huriez - Lille, Lille

92110

Hôpital Beaujon - Clichy, Clichy

94800

Hôpital Paul Brousse - Villejuif, Villejuif

404327

China Medical University Hospital, Taichung

362-0806

Saitama Cancer Center, Kitaadachi-gun

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY