NCT06245889View on ClinicalTrials.gov

PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 1, 2024

Primary Completion Date

June 30, 2029

Study Completion Date

June 30, 2030

Conditions
Triple Negative Breast Cancer
Interventions
DRUG

Paclitaxel

chemotherapy

DRUG

Carboplatin

chemotherapy

DRUG

Pembrolizumab

immunotherapy

DRUG

Doxorubicin

additional chemotherapy - neoadjuvant or adjuvant rescue

DRUG

Cyclophosphamide

additional chemotherapy - adjuvant rescue

DRUG

Olaparib

adjuvant rescue

DRUG

Capecitabine

adjuvant rescue

Trial Locations (2)

21287

RECRUITING

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

RECRUITING

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

Sponsors
All Listed Sponsors
collaborator

Breast Cancer Research Foundation

OTHER

lead

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER