Physiologic Pacing for Symptomatic First-Degree Heart Block

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

June 30, 2025

Conditions
Symptomatic First-degree Heart Block
Interventions
DEVICE

Dual chamber Medtronic pacemaker implantation.

"All patients will undergo a dual chamber Medtronic pacemaker implantation meeting approved indications for pacemaker implantation per Centers for Medicare \& Medicaid Services (CMS) guidelines.~Pacemaker Model: Azure XT W1DR01. Right ventricular lead model: Medtronic 3830."

OTHER

DDD-50 pacing program

This device programming attempts to increase the amount of ventricular pacing via the Medtronic 3830 lead. Since the enrolled patients have a prolonged PR interval, this programming attempts to synchronic atrial and ventricular contractions.

OTHER

AAI-DDD 50 pacing program

This device programming attempts to encourage native conduction and minimize ventricular pacing via the Medtronic 3830 lead. This programming attempts to minimize ventricular pacing, which has been associated with worse outcomes by causing ventricular dyssynchrony between the left and right ventricles.

Trial Locations (1)

37203

RECRUITING

Ascension Saint Thomas Midtown, Nashville

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Medtronic

INDUSTRY

lead

Ascension Health

INDUSTRY