Role of Insulin Action in Psoriasis Pathogenesis

RecruitingOBSERVATIONAL
Enrollment

18

Participants

Timeline

Start Date

February 2, 2024

Primary Completion Date

April 30, 2027

Study Completion Date

May 31, 2027

Conditions
PsoriasisPlaque PsoriasisInsulin ResistancePreDiabetesOverweight and Obesity
Interventions
DIAGNOSTIC_TEST

Oral glucose tolerance test (OGTT)

Participants ingest 75 g of glucose in 10 fl oz aqueous solution (fruit flavored) after an overnight fast. Blood is drawn at baseline (t = 0 min) and at 120 min after ingestion. This test is non-experimental.

PROCEDURE

Skin punch biopsy

Punch biopsies are taken from lesional (psoriatic) and non-lesional skin after an overnight fast and at 120 min after ingestion of glucose during OGTT. This procedure is non-experimental.

Trial Locations (1)

10032

RECRUITING

Columbia University Irving Medical Center, New York

All Listed Sponsors
lead

Columbia University

OTHER