Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002)

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

304

Participants

Timeline

Start Date

February 28, 2024

Primary Completion Date

June 17, 2025

Study Completion Date

June 17, 2025

Conditions
Advanced Solid Tumors
Interventions
BIOLOGICAL

MK-1200

IV Infusion

DRUG

Antiemetic

One or more prophylactic antiemetic(s) (e.g. 5-HT3 receptor antagonists, dexamethasone, neurokinin-1 receptor antagonists, etc.) may be selected based on previous response of participants to antiemetic medications and individual factors, and will be administered per approved product label prior to MK-1200 infusion

Trial Locations (16)

3004

The Alfred Hospital ( Site 0103), Melbourne

22908

University of Virginia Health System-Hematology-Oncology ( Site 0009), Charlottesville

40202

The University of Louisville, James Graham Brown Cancer Center ( Site 0004), Louisville

49546

START Midwest ( Site 0014), Grand Rapids

78229

South Texas Accelerated Research Therapeutics (START) ( Site 0005), San Antonio

84119

START Mountain Region ( Site 0015), West Valley City

100142

Beijing Cancer hospital-Digestive Oncology ( Site 0401), Beijing

223300

First Huai'an Hospital Affiliated to Nanjing Medical University ( Site 0415), Huai'an

350000

Fujian Cancer Hospital-oncology department ( Site 0409), Fuzhou

3109601

Rambam Health Care Campus-Oncology Division ( Site 0602), Haifa

4941492

Rabin Medical Center-Oncology ( Site 0603), Petah Tikva

5265601

Sheba Medical Center ( Site 0605), Ramat Gan

6423906

Sourasky Medical Center ( Site 0601), Tel Aviv

8420383

Bradfordhill-Clinical Area ( Site 0301), Santiago

9112001

Hadassah Medical Center ( Site 0604), Jerusalem

06351

Samsung Medical Center-Division of Hematology/Oncology ( Site 1003), Seoul

All Listed Sponsors
lead

Merck Sharp & Dohme LLC

INDUSTRY

NCT06242691 - Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002) | Biotech Hunter | Biotech Hunter