Lenvatinib Plus Toripalimab for Platinum-Resistant Recurrent Ovarian Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

February 1, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2025

Conditions
Recurrent Ovarian Carcinoma
Interventions
DRUG

Lenvatinib+Toripalimab.

Adjustment of Medication Dosage: Throughout the course of treatment, adjustments should be made exclusively to the dosage of the drug Lenvatinib.The starting dosage for lenvatinib is 8 mg, administered orally once a day for a period of four weeks. If no adverse reactions are observed, the dosage can be escalated to 12 mg for individuals weighing over 60 kg. However, if the patient experiences intolerable side effects, the dosage should be decreased back to 8 mg.For individuals weighing less than 60 kg, the maximum dosage is 8 mg per day. Should adverse reactions become intolerable, the dosage may be decreased to 4 mg per day.Withdrawal from the study if still intolerable.

Trial Locations (1)

100730

RECRUITING

Peking Union Medical College Hospital, Beijing

All Listed Sponsors
collaborator

The Second Affiliated Hospital of Dalian Medical University

OTHER

collaborator

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

lead

Peking Union Medical College Hospital

OTHER