Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

NARecruitingINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

February 23, 2023

Primary Completion Date

December 23, 2025

Study Completion Date

February 15, 2026

Conditions
Non-small Cell Lung CancerBrain MetastasesEGFR Gene Mutation
Interventions
COMBINATION_PRODUCT

Nitroglycerin

Patients in the intervention group will receive four 8mg-patches (36 mg final dose) of transdermal nitroglycerin with 10 mg release in 24 hours, for 24 hours with 12-hour rest intervals (to avoid receptor saturation) during treatment with radiation therapy (30 Gy in 10 fractions, or 10 days of treatment).

Trial Locations (1)

14080

RECRUITING

Instituto Nacional de Cancerologia, Mexico City

All Listed Sponsors
lead

Instituto Nacional de Cancerologia de Mexico

OTHER