Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application

CompletedOBSERVATIONAL
Enrollment

95

Participants

Timeline

Start Date

August 1, 2021

Primary Completion Date

April 28, 2022

Study Completion Date

December 31, 2023

Conditions
COVID-19Outcome, FatalTocilizumabInterleukin 6Critically Ill
Interventions
DRUG

treated without (N), with casirivimab / imdevimab (C) or tocilizumab (T), solely, or in combination of both (C + T)

IgG seronegative SARSCoV2-Spike antibody (\< 0,80 U/ml) COVID-19 patients were treated with 1 dose of subcutaneous casirivimab and imdevimab, 1200 mg (600 mg of each). Patients with CRP \> 75 mg/l or IL-6 \> 75 ng/l were treated with one dose of intravenous tocilizumab 8 mg/kg body weight

Trial Locations (1)

89070

Clinic of Anesthesiology, Ulm

All Listed Sponsors
lead

University of Ulm

OTHER

NCT06233357 - Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application | Biotech Hunter | Biotech Hunter