A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

PHASE3WithdrawnINTERVENTIONAL
0
Timeline

Start Date

May 3, 2024

Primary Completion Date

November 16, 2025

Study Completion Date

September 21, 2030

Conditions
Multiple Myeloma
Interventions
DRUG

Alnuctamab

Specified dose on specified days

DRUG

Pomalidomide

Specified dose on specified days

DRUG

Daratumumab

Specified dose on specified days

DRUG

Elotuzumab

Specified dose on specified days

DRUG

Carfilzomib

Specified dose on specified days

DRUG

Dexamethasone

Specified dose on specified days

Trial Locations (170)

0

Local Institution - 0413, Beijing

Local Institution - 0187, Kayseri

1088

Local Institution - 0104, Budapest

1090

Local Institution - 0332, Vienna

1097

Local Institution - 0105, Budapest

1474

Local Institution - 0137, Løenskog

1629

Local Institution - 0262, Pilar

1888

Local Institution - 0222, San Juan Bautista

1900

Local Institution - 0001, La Plata

2109

Local Institution - 0246, Macquarie University

2170

Local Institution - 0260, Liverpool

2298

Local Institution - 0022, Waratah

2930

Local Institution - 0284, Brasschaat

3000

Local Institution - 0286, Leuven

3004

Local Institution - 0018, Melbourne

3010

Local Institution - 0336, Bern

3065

Local Institution - 0003, Melbourne

3100

Local Institution - 0333, Sankt Pölten

3128

Local Institution - 0021, Box Hill

3168

Local Institution - 0019, Clayton

4120

Local Institution - 0397, Brisbane

4400

Local Institution - 0103, Nyíregyháza

4800

Local Institution - 0280, Verviers

5020

Local Institution - 0334, Salzburg

5021

Local Institution - 0115, Bergen

5530

Local Institution - 0279, Yvoir

6020

Local Institution - 0337, Innsbruck

8063

Local Institution - 0338, Zurich

9007

Local Institution - 0411, Sankt Gallen

9700

Local Institution - 0108, Szombathely

10065

Local Institution - 0396, New York

11042

Local Institution - 0430, Lake Success

11407

Local Institution - 0202, Jerez de la Frontera

12462

Local Institution - 0136, Chaïdári

12808

Local Institution - 0012, Prague

13620

Local Institution - 0240, Seongnam

15224

Local Institution - 0437, Pittsburgh

15706

Local Institution - 0007, Santiago de Compostela

20007

Local Institution - 0434, Washington D.C.

20025

Local Institution - 0294, Legnano

20162

Local Institution - 0265, Milan

20889

Local Institution - 0441, Bethesda

21218

Local Institution - 0324, Baltimore

22763

Local Institution - 0339, Hamburg

30120

Local Institution - 0234, El Palmar, Murcia

31008

Local Institution - 0008, Pamplona

31100

Local Institution - 0118, Toulouse

34214

Local Institution - 0325, Stanbul

34295

Local Institution - 0225, Montpellier

35100

Local Institution - 0188, Izmir

35294

Local Institution - 0151, Birmingham

37007

Local Institution - 0006, Salamanca

40207

Local Institution - 0439, Saint Matthews

44000

Local Institution - 0085, Nantes

44109

Local Institution - 0199, Cleveland

45220

Local Institution - 0306, Cincinnati

46026

Local Institution - 0009, Valencia

47014

Local Institution - 0096, Meldola

49201

Local Institution - 0221, Busan

54511

Local Institution - 0224, Vandœuvre-lès-Nancy

57201

Local Institution - 0420, Watertown

59000

Local Institution - 0084, Lille

59102

Local Institution - 0435, Billings

67214

Local Institution - 0433, Wichita

69120

Local Institution - 0331, Heidelberg

69310

Local Institution - 0192, Pierre-Bénite

70112

Local Institution - 0323, New Orleans

72076

Local Institution - 0330, Tübingen

90095

Local Institution - 0088, Los Angeles

90127

Local Institution - 0410, Palermo

94305

Local Institution - 0358, Stanford

98109

Local Institution - 0405, Seattle

100020

Local Institution - 0230, Beijing

100034

Local Institution - 0040, Beijing

102200

Local Institution - 0366, Changping

110004

Local Institution - 0044, Shenyang

122011

Local Institution - 0362, Gurugram

200032

Local Institution - 0273, Shanghai

200081

Local Institution - 0421, Shanghai

210000

Local Institution - 0055, Nanjing

215006

Local Institution - 0067, Suzhou

221006

Local Institution - 0377, Xuzhou

226014

Local Institution - 0399, Lucknow

250014

Local Institution - 0077, Jinan

250117

Local Institution - 0083, Jinan

266011

Local Institution - 0367, Qingdao

300052

Local Institution - 0056, Tianjin

300308

Local Institution - 0422, Tianjin

310003

Local Institution - 0070, Hangzhou

Local Institution - 0203, Hangzhou

400016

Local Institution - 0057, Chongqing

410011

Local Institution - 0062, Changsha

410013

Local Institution - 0053, Changsha

430030

Local Institution - 0075, Wuhan

450008

Local Institution - 0041, Zhengzhou

500052

Local Institution - 0171, Brasov

510060

Local Institution - 0066, Guangzhou

510120

Local Institution - 0080, Guangzhou

510515

Local Institution - 0226, Guangzhou

518036

Local Institution - 0368, Shenzhen

530040

Local Institution - 0370, Visakhapatnam

560092

Local Institution - 0403, Bangalore

700094

Local Institution - 0398, Kolkata

710004

Local Institution - 0072, Xi'an

7500921

Local Institution - 0030, Santiago

7580206

Local Institution - 0027, Santiago

7620002

Local Institution - 0026, Santiago

7650568

Local Institution - 0029, Santiago

59025050

Local Institution - 0351, Natal

06520

Local Institution - 0355, New Haven

07601

Local Institution - 0157, Hackensack

07901

Local Institution - 0359, Summit

02903

Local Institution - 0352, Providence

75390-88520

Local Institution - 0168, Dallas

C1118AAT

Local Institution - 0002, Buenos Aires

30110-022

Local Institution - 0274, Belo Horizonte

01509-010

Local Institution - 0369, São Paulo

22250-905

Local Institution - 0291, Rio de Janeiro

05652-900

Local Institution - 0211, São Paulo

T2N 4N2

Local Institution - 0417, Calgary

T6G1Z2

Local Institution - 0423, Edmonton

N6A 5W9

Local Institution - 0402, London

M5G 2M9

Local Institution - 0395, Toronto

H1T 2M4

Local Institution - 0031, Montreal

H2X 1P1

Local Institution - 0098, Montreal

071030

Local Institution - 0365, Baoding

050051

Local Institution - 0082, Shijiazhuang

030000

Local Institution - 0245, Taiyuan

625 00

Local Institution - 0013, Brno

779 00

Local Institution - 0247, Olomouc

01307

Local Institution - 0335, Dresden

04103

Local Institution - 0329, Leipzig

115 28

Local Institution - 0004, Athens

T12 E8YV

Local Institution - 0281, Cork

D04 N2E0

Local Institution - 0371, Dublin

D08 E9P6

Local Institution - 0285, Dublin

V94 F858

Local Institution - 0269, Limerick

446-8602

Local Institution - 0409, Anjo

467-8602

Local Institution - 0387, Nagoya

296-0041

Local Institution - 0407, Kamogawa

277-8577

Local Institution - 0385, Kashiwa

259-1193

Local Institution - 0386, Isehara

589-8511

Local Institution - 0390, Ōsaka-sayama

321-0293

Local Institution - 0381, Shimotsuga

135-8550

Local Institution - 0382, Koto

030-8553

Local Institution - 0419, Aomori

260-8677

Local Institution - 0383, Chiba

860-8556

Local Institution - 0391, Kumamoto

602-8566

Local Institution - 0389, Kyoto

701-1192

Local Institution - 0388, Okayama

150-8935

Local Institution - 0384, Tokyo

0450

Local Institution - 0193, Oslo

1099-023

Local Institution - 0242, Lisbon

1649-035

Local Institution - 0415, Lisbon

1500-650

Local Institution - 0255, Lisbon

022328

Local Institution - 0169, Bucharest

050098

Local Institution - 0414, Bucharest

03080

Local Institution - 0036, Seoul

05505

Local Institution - 0239, Seoul

06351

Local Institution - 0034, Seoul

06591

Local Institution - 0035, Seoul

08916

Local Institution - 0011, Badalona

501 82

Local Institution - 0114, Borås

413 45

Local Institution - 0111, Gothenburg

06200

Local Institution - 0375, Ankara

SO16 0YD

Local Institution - 0349, Southampton

NW1 2PG

Local Institution - 0342, London

CF14 4XW

Local Institution - 0350, Cardiff

DE22 3NE

Local Institution - 0344, Derby

M20 4BX

Local Institution - 0343, Manchester

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY

NCT06232707 - A Study to Evaluate Efficacy and Safety of Alnuctamab Compared to Standard of Care Regimens in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) | Biotech Hunter | Biotech Hunter