NCT06232629View on ClinicalTrials.gov

Towards Noninvasive DBS of the Basal Ganglia in Parkinson's Disease Using TUS

NAActive, not recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 1, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Parkinson DiseaseDystonia
Interventions
DEVICE

TUS Active

Bilateral GPis will be sonicated using NeuroFUS device for either two minutes (5Hz protocol) or 40 seconds (10 Hz protocol) per hemisphere and with 30 W/cm2 Isppa

DEVICE

TUS Sham

"Passive sham: Bilateral GPis will be sonicated using NeuroFUS device for two minutes (5Hz protocol) or 40 seconds (10 Hz protocol) per hemisphere and 0 W/cm2 Isppa~Active sham: Bilateral occipital cortices will be sonicated using NeuroFUS device for two minutes (5Hz protocol) or 40 seconds (10 Hz protocol) per hemisphere and 30 W/cm2 Isppa"

Trial Locations (1)

M5T 2S8

Toronto Western Hospital, Toronto

All Listed Sponsors
lead

University Health Network, Toronto

OTHER

NCT06232629 - Towards Noninvasive DBS of the Basal Ganglia in Parkinson's Disease Using TUS | Biotech Hunter | Biotech Hunter