A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK112 in Patients With Non-Small Cell Lung Cancer

PHASE1RecruitingINTERVENTIONAL
Enrollment

164

Participants

Timeline

Start Date

February 22, 2024

Primary Completion Date

March 31, 2027

Study Completion Date

March 31, 2028

Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG

ABSK112

In the escalation part, patients will receive a single dose of oral ABSK112 on Cycle1 Day1 only, and then patients will continuously receive ABSK112 once daily (QD) or twice daily (BID) in subsequent cycles. In the expansion part, patients will each be treated at the selected RDE dose level.

Trial Locations (14)

90212

RECRUITING

Precision NextGen Oncology, Beverly Hills

Unknown

NOT_YET_RECRUITING

Anhui Chest Hospital, Hefei

NOT_YET_RECRUITING

Fujian Cancer Hospital, Fuzhou

NOT_YET_RECRUITING

The first Affiliated Hospital of Xi'an Jiaotong University, Xi'an

NOT_YET_RECRUITING

Harbin Medical University Cancer Hospital, Harbin

NOT_YET_RECRUITING

Henan Cancer Hospital, Zhengzhou

NOT_YET_RECRUITING

Union Hospital Tongji Medical College Huzhong University of Science and Techology, Wuhan

NOT_YET_RECRUITING

Hunan Cancer Hospital, Changsha

NOT_YET_RECRUITING

The first Affiliated Hospital of Nanchang University, Nanchang

NOT_YET_RECRUITING

Jilin Cancer Hospital, Changchun

NOT_YET_RECRUITING

Central Hospital Affiliated to Shangdong of First Medical University, Jinan

RECRUITING

Shanghai Chest Hospital, Shanghai

NOT_YET_RECRUITING

Sichuan Cancer Hospital, Chengdu

NOT_YET_RECRUITING

Zhejiang Caner Hospital, Hangzhou

Sponsors
All Listed Sponsors
lead

Abbisko Therapeutics Co, Ltd

INDUSTRY

NCT06225804 - A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK112 in Patients With Non-Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter