Augmenting Rehabilitation Outcomes and Functional Neuroplasticity Using Epidural Stimulation of Cervical Spinal Cord

NARecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

August 6, 2024

Primary Completion Date

January 1, 2027

Study Completion Date

January 1, 2027

Conditions
Spinal Cord InjuriesCervical Spinal Cord Injury
Interventions
DEVICE

Epidural Spinal Stimulation (ESS)

ESS will be delivered using The CoverEdgeX 32 Surgical Lead at frequencies of 0.2 to 60 Hz with intensity up to 10 mA, adjusted to induce motor threshold responses in the target muscle for the above motor task (e.g., biceps brachii for elbow flexion) \[31-33\]. The ESS controller will only be operated by trained study team members. Therefore, stimulation will only be delivered during study visits. Stimulation will be administered for a maximum duration of 1 hour total per visit, varying according to the individual's tolerance and fatigue levels, with 5 - 10 minutes breaks interspersed between intervals of stimulation.

Trial Locations (1)

77030

RECRUITING

The Methodist Hospital Research Institute, Houston

All Listed Sponsors
lead

The Methodist Hospital Research Institute

OTHER