500
Participants
Start Date
January 1, 2024
Primary Completion Date
December 31, 2028
Study Completion Date
December 31, 2029
Homoharringtonine
3mg/m2/day for weighing \>10kg, 0.1mg/kg/day for weighing ≤10kg, d1-7, ivgtt, qd, more than 6 hours
Cytarabine
100mg/m2/q12h for weighing \>10kg, 3.3mg/kg/q12h for weighing ≤10kg, d1-7, ivgtt, q12h, more than 30 minutes in SDC group; 10mg/m2/q12h for weighing \>10kg, 0.33mg/kg/q12h for weighing ≤10kg, d1-10, s.c.,q12h (the first dose at 8 am) in the LDC group;
Etoposide
100mg/m2/d for weighing \>10kg, 3.3mg/kg/d for weighing ≤ 10kg, d1-5, ivgtt, qd, more than 4 hours
Venetoclax
100mg/m2/d for weighing \>10kg, 3.33mg/kg/d for weighing ≤10kg, d12-25, po, qd
Mitoxantrone hydrochloride liposome
5mg/m2/d for weighing \>10kg, 0.17mg/kg/d for weighing ≤ 10kg, d1, 3, 5, ivgtt, qod, more than 2 hours at 10 am.
Recombinant Human Granulocyte Colony-Stimulating Factor
5ug/kg/d, d1-10, s.c., qd, at 1pm
Idarubicin Hydrochloride
3mg/m2/day for weighing \>10kg, 0.1mg/kg/day for weighing ≤ 10kg, d1-7, ivgtt, qd, more than 6 hours.
Sorafenib
100mg/m2/day for weighing \>10kg, 3.3mg/kg/day for weighing ≤10kg, from identification, po, qd
Gilteritinib
20mg/m2/day for weighing \>10kg, 0.7mg/kg/day for weighing ≤ 10kg, from identification, po, qd
Avapritinib
50mg/m2/day for weighing bodyweight \>10kg, 1.65mg/kg/day for weighing ≤ 10kg, po, qd
NOT_YET_RECRUITING
Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing
NOT_YET_RECRUITING
Children's Hospital Of Fudan University, Shanghai
RECRUITING
Children's Hospital of Soochow University, Suzhou
NOT_YET_RECRUITING
Xuzhou Children's Hospital, Xuzhou
NOT_YET_RECRUITING
First Affiliated Hospital Of University of Science and Technology of China, Hefei
NOT_YET_RECRUITING
The Second Hospital of Anhui Medical University, Hefei
NOT_YET_RECRUITING
Qilu Hospital of Shandong University, Jinan
NOT_YET_RECRUITING
Third Xiangya Hospital of Central South University, Changsha
NOT_YET_RECRUITING
XiangYa Hospital Central South University, Changsha
NOT_YET_RECRUITING
The First Affiliated Hospital of Zhengzhou University, Zhengzhou
NOT_YET_RECRUITING
Kaifeng Children's Hospital, Kaifeng
NOT_YET_RECRUITING
Guangzhou Women and Children Medical Center, Guangzhou
NOT_YET_RECRUITING
The First Affiliated Hospital of Guangxi Medical University, Nanning
Children's Hospital of Soochow University
OTHER