Hemodynamic Instability of Patient With Spontaneous Subarachnoid Hemorrhage

RecruitingOBSERVATIONAL
Enrollment

90

Participants

Timeline

Start Date

January 15, 2024

Primary Completion Date

January 31, 2025

Study Completion Date

July 31, 2026

Conditions
Subarachnoid Hemorrhage, SpontaneousSubarachnoid Hemorrhage, Aneurysmal
Interventions
DIAGNOSTIC_TEST

biomarkers

"Serum tests for specific cardiac troponin (cTPI), neuron-specific enolase (NSE), natriuretic peptides (NT-ProBNP), S100 protein (S100B), Soluble Suppressor of Tumorigenesis-2 (sST2), and soluble urokinase plasminogen activator receptor (suPAR) tests will be performed, as well as urinary tests for epinephrine and norepinephrine. On these samples, conducted according to clinical practice, additional measurements will also be taken for glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase (UCH-L1) as specific study biomarkers on blood samples.~All samples will be collected within 24 hours of admission to the Emergency Department (T0) and after 72 hours (T1). A sample at day 7 (T2) will be taken."

Trial Locations (1)

00168

RECRUITING

Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER