Development and Evaluation of Computerized Chemosensory Based Orbitofrontal Networks Training for Treatment of Pain

PHASE1CompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

April 27, 2023

Primary Completion Date

September 15, 2023

Study Completion Date

September 15, 2023

Conditions
Chronic PainLow Back Pain
Interventions
COMBINATION_PRODUCT

Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) short burst paradigm

The CBOT device is designed to stimulate intensive neural activity in the medial orbitofrontal regions over long periods of time.

COMBINATION_PRODUCT

Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) long burst paradigm

The CBOT device is designed to stimulate intensive neural activity in the lateral orbitofrontal regions and networks over long periods of time.

COMBINATION_PRODUCT

Computerized Chemosensory-Based Orbitofrontal Cortex Training plus beta caryophyllene (CBOT-Plus)

CBOT device enhanced with BCP.

COMBINATION_PRODUCT

Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT)

CBOT device administering continuous olfactory stimuli (i.e., not programmed for short or long burst), and without BCP enhancement.

Trial Locations (1)

20060

Howard University, Washington D.C.

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

collaborator

Howard University

OTHER

collaborator

Georgetown University

OTHER

lead

Evon Medics LLC

INDUSTRY

NCT06218407 - Development and Evaluation of Computerized Chemosensory Based Orbitofrontal Networks Training for Treatment of Pain | Biotech Hunter | Biotech Hunter