Multicenter Observational Study Taulí-T1 Classification for the Management of pT1 Rectal Adenocarcinoma

RecruitingOBSERVATIONAL
Enrollment

317

Participants

Timeline

Start Date

October 2, 2023

Primary Completion Date

October 6, 2025

Study Completion Date

January 5, 2026

Conditions
Rectal Cancer Stage I
Interventions
DIAGNOSTIC_TEST

Taulí-T1 versus conventional classifications

All the slides of each case will be reviewed, selecting the one that contains the most invasive section, and this will be digitized to take measurements in micrometers with greater precision. To measure the degree of infiltration, the measurement of residual healthy submucosa (hrSB) will be used, which is the distance between the point of greatest infiltration and the muscularis propria. The total thickness of the submucosa in the tumor area will also be measured, taking as a reference the muscularis of the mucosa or, in its absence, the surface of the lesion, to calculate the percentage of infiltration of the submucosa. This percentage will be calculated as the inverse percentage of invasion with respect to the hrSB: (total thickness of the submucosa - hrSB / total thickness of the submucosa) x 100. The qualitative categories will be obtained: sm1 (\< 33.3%), sm2 (33.3% - 66.6%) and sm3 (\> 66.6%). Measurements will be also taken in micrometers for the conventional classifications.

Trial Locations (1)

08208

RECRUITING

Hospital Universitario Parc Tauli de Sabadell, Sabadell

Sponsors
All Listed Sponsors
lead

Corporacion Parc Tauli

OTHER