Emergency Delirium in Pediatrics Undergoing Tonsillectomy and Adenoidectomy

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

September 30, 2024

Study Completion Date

October 31, 2024

Conditions
Emergence Delirium
Interventions
DRUG

Dexmedetomidine and Midazolam

"This will be a prospective, double-blind, randomized controlled study conducted between October 2023and June 2024 .~Patients aged( 2\_12) years, American Society of Anesthesiologists class (ASA) I or II, scheduled for tonsillectomy with and without adenoidectomy will be randomized to receive intravenous dexmedetomidine 0.5 μg/kg Or intravenous midazolam 0.1 mg /kg(Group A) or (Group B) over 10 minutes after induction of anesthesia. The primary outcome is the incidence of ED within 30 minutes after extubation. Other outcomes are the incidence of pain, extubation time, post-anesthesia care unit (PACU) length of stay after extubation, adverse events, and the incidence of negative postoperative behavioral changes (NPOBCs)."

All Listed Sponsors
lead

Esraa Abdel Azez Soltan Mohamed Zayed

OTHER

NCT06215768 - Emergency Delirium in Pediatrics Undergoing Tonsillectomy and Adenoidectomy | Biotech Hunter | Biotech Hunter