A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

January 15, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG

VRG50635

"Part 1, no study drug will be administered.~Part 2, the starting dose is 400 mg for 8 weeks (Treatment Period 1) and doses will be escalated to 600 mg for 8 weeks (Treatment Period 2) and 800 mg for 8 weeks (Treatment Period 3).~Part 3, each participant will continue receiving treatment with the highest tolerated dose achieved in Part 2 for up to 40 weeks."

Trial Locations (7)

Unknown

UZ Leuven, Leuven

H3A 2B4

Stan Cassidy Centre for Rehabilitation (Horizon NB), Montreal

The Neuro - Montréal Neurological Institute-Hospital, Montreal

FI-70210

University of Eastern Finland, Brain Research Unit, Kuopio

FI-00029

Helsinki University Hospital, Helsinki

FI-20520

Turku University Hospital, Turku

3584 CX

University Medical Center Utrecht, Utrecht

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Verge Genomics

INDUSTRY

NCT06215755 - A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS) | Biotech Hunter | Biotech Hunter