NCT06214910View on ClinicalTrials.gov

ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa

NAActive, not recruitingINTERVENTIONAL
Enrollment

540

Participants

Timeline

Start Date

February 20, 2024

Primary Completion Date

February 10, 2026

Study Completion Date

December 31, 2026

Conditions
TuberculosisHIV I Infection
Interventions
OTHER

Community-delivered TB preventive therapy (TPT) - 3 months weekly isoniazid plus rifapentine (3HP)

Participants randomized to this arm will receive the entire supply of TB preventive therapy (TPT) at enrollment.

OTHER

Clinic-link TPT

Participants receive 2-week supply of TPT at initiation, then continue to receive remainder of TPT course at clinic (including refills).

Trial Locations (1)

Unknown

Human Sciences Research Council, Sweetwaters

All Listed Sponsors
collaborator

Human Sciences Research Council

OTHER_GOV

collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

University of Washington

OTHER