Asymmetrical Versus Conventional High-flow Nasal Cannula in Acute Respiratory Failure

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 20, 2024

Primary Completion Date

January 15, 2025

Study Completion Date

May 15, 2025

Conditions
Acute Hypoxemic Respiratory FailureAcute Hypercapnic Respiratory Failure
Interventions
DEVICE

Experimental: Asymmetrical high-flow nasal cannula

Asymmetrical high-flow nasal cannula will be set at 40 and 60 L/min in a random order. Temperature will be set at 37 degree celsius and inspired oxygen fraction (FiO2) will be adjusted to maintain oxygen saturation by pulse oximetry (SpO2) \>/= 94% in acute hypoxemic patients and between 92-94% in acute hypercapnic COPD patients

DEVICE

Active comparator: Conventional high-flow nasal cannula

Conventional high-flow nasal cannula will be set at 40 and 60 L/min in a random order. Temperature will be set at 37 degree celsius and FiO2 will be adjusted to maintain SpO2 \>/= 94% in acute hypoxemic patients and between 92-94% in acute hypercapnic COPD patients

Trial Locations (1)

10700

RECRUITING

Faculty of Medicine Siriraj Hospital, Bangkok Noi

All Listed Sponsors
lead

Siriraj Hospital

OTHER