Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty

PHASE3RecruitingINTERVENTIONAL
Enrollment

288

Participants

Timeline

Start Date

September 9, 2024

Primary Completion Date

February 1, 2026

Study Completion Date

April 1, 2026

Conditions
Postsurgical Pain
Interventions
DRUG

Multiprofen-CC™ plus standard treatment

Multiprofen-CC™ \[ketoprofen (10%), baclofen (5%), amitriptyline (2%), and lidocaine (5%)\] Dose: 1.0g, 3 times per day for 6 weeks after surgery

OTHER

Placebo plus standard treatment

The placebo is the base cream with no medicinal ingredients to be applied 3 times per day for 6 weeks after surgery

Trial Locations (2)

L8N 4A6

RECRUITING

St. Joseph's Healthcare Hamilton, Hamilton

L6M 0L8

NOT_YET_RECRUITING

Oakville Trafalgar Memorial Hospital, Oakville

Sponsors
All Listed Sponsors
collaborator

McMaster University

OTHER

lead

KAZM Pharmaceuticals Inc.

INDUSTRY