Cadonilimab Plus CapeOX as First-Line Treatment for Advanced GC/GEJC With High TMEscore

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

April 30, 2024

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
Gastric Cancer
Interventions
DRUG

Cadonilimab plus CapeOX chemotherapy

Cadonilimab plus oxaliplatin/capecitabine (CapeOX) chemotherapy as first-line treatment in patients with advanced gastric cancer or gastro-esophageal junction adenocarcinoma: Cadonilimab 10mg/kg, iv, q3w + oxaliplatin 130mg/m2, vd, d1 + capecitabine 1000mg/m2, po, bid, d1-d4, q3w (3 weeks as a cycle, a maximum of 8 cycles of treatment). Then the maintenance treatment phase with tislelizumab + lenvatinib is entered, and the specific dosage is the same as the treatment period.

Trial Locations (1)

510515

Nanfang Hospital, Southern Medical University, Guangzhou

All Listed Sponsors
lead

Nanfang Hospital, Southern Medical University

OTHER

NCT06202716 - Cadonilimab Plus CapeOX as First-Line Treatment for Advanced GC/GEJC With High TMEscore | Biotech Hunter | Biotech Hunter