120
Participants
Start Date
November 15, 2024
Primary Completion Date
December 30, 2025
Study Completion Date
March 30, 2026
Nebivolol+ Standard care arm
This arm will receive tablet Nebivolol 2.5 mg OD uptitrated at 2 weeks to 5 mg and at 4 weeks if well tolerated to 10 mg/day which the participant will continue upto week 24
Epalrestat + Alpha Lipoic Acid +Standard care
This arm will receive tablet Epalrestat -150mg OD+ cap Alpha Lipoic Acid 600mg OD for 24 weeks.
Standard care alone
Patients in this arm will receive standard care as judged by their treating physicians which is generally pain modifying treatment.
RECRUITING
St John's Medical College Hospital, Bangalore
NOT_YET_RECRUITING
St John's Research Institute, Bangalore
St. John's Research Institute
OTHER