Neoadjuvant Adebrelimab Plus Dalpiciclib in Head and Neck Squamous Cell Carcinoma

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG

Adebrelimab and dalpiciclib

Before surgery, the eligible patients received 3 cycles of adebrelimab (1200 mg intravenously every 3 weeks, Day 1, 22 and 43) and 2 cycles of dalpiciclib (150 mg, po, every 4 weeks, day 1-21 and 29-49). Administration dose adjustments were permitted according to the haematological or non-haematological toxicity.

All Listed Sponsors
lead

Zhongzheng Xiang

OTHER