25
Participants
Start Date
March 6, 2024
Primary Completion Date
February 28, 2027
Study Completion Date
February 28, 2027
ketone ester
500 mg/kg of ketone ester administered approximately 1 hour prior to the maximal exercise testing and 250 mg/kg administered approximately 30 minutes prior to submaximal exercise testing
placebo
ketone-free placebo administered approximately 1 hour prior to the maximal exercise testing and ketone-free placebo administered approximately 30 minutes prior to submaximal exercise testing
Duke University, Durham
Lead Sponsor
American Heart Association
OTHER
National Institutes of Health (NIH)
NIH
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Duke University
OTHER