Evaluation of a Direct Oral Penicillin Challenge in a Rural Community

Patients are screened to confirm they are low risk for a penicillin allergy

Low risk participants are given a low-dose of oral penicillin followed by 60 minutes of observation

Participants who have taken the low dose of oral penicillin and have had no reaction are provided a second higher dose of penicillin (250mg) and observed for 60 minutes.

Participants who have no reaction after 28 days have their penicillin allergy label removed from their electronic medical record and hospital record.