Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma

PHASE1RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

November 20, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

November 30, 2026

Conditions
Cervical Intraepithelial NeoplasiaInvasive Cervical Cancer
Interventions
DRUG

Fenofibrate

Fenofibrate is an FDA approved drug for cardiovascular indications and have decades of data supporting a favorable safety profile event with chronic use.

PROCEDURE

Cervical Conization

Cold knife conization or loop electrosurgical excision to remove cells and tissue in the cervix

PROCEDURE

Hysterectomy

In a hysterectomy, the uterus, cervix, both ovaries, both fallopian tubes, and nearby tissue are removed.

RADIATION

Chemoradiation

Chemotherapy uses anti cancer (cytotoxic) drugs to destroy cancer cells. The drugs circulate throughout the body in the bloodstream. Radiotherapy uses high energy waves similar to x-rays to kill cancer cells.

Trial Locations (1)

44106

RECRUITING

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland

All Listed Sponsors
lead

Lindsay Ferguson, MD

OTHER