Comparison of Aerosol Inhalation and Intravenous Glucocorticoid in the Treatment of Severe AECOPD

NAEnrolling by invitationINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

October 1, 2021

Primary Completion Date

December 31, 2024

Study Completion Date

July 31, 2025

Conditions
Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions
DRUG

aerosol inhalation of glucocorticoids

Patients with severe AECOPD were continuously recruited from the care unit of Respiratory and Critical Care Medicine Department of the First Hospital of Jilin University to conduct a randomized cohort study, which was divided into aerosol inhalation group and intravenous glucocorticoid group. Subjects in the intravenous hormone group received 40mg methylprednisolone (dissolved in 0.9% normal saline /5% glucose injection 50ml) intravenously once a day. It lasts for 5 days. The atomized inhalation

DRUG

intravenous injection of glucocorticoids

Patients with severe AECOPD were continuously recruited from the care unit of Respiratory and Critical Care Medicine Department of the First Hospital of Jilin University to conduct a randomized cohort study, which was divided into aerosol inhalation group and intravenous glucocorticoid group. Subjects in the intravenous hormone group received 40mg methylprednisolone (dissolved in 0.9% normal saline /5% glucose injection 50ml) intravenously once a day. It lasts for 5 days. The atomized inhalation

Trial Locations (1)

130021

The First Hospital of Jilin University, Changchun

All Listed Sponsors
collaborator

Jilin University

OTHER

lead

Dong Yang

OTHER