Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007)

PHASE2RecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2028

Conditions
Locally Advanced Esophageal Squamous Cell Carcinoma
Interventions
DRUG

S-1

Patients received S-1 administration, 70mg/m2 per day, orally on days 1 to 14 and 29 to 42 during radiotherapy.

DRUG

Toripalimab

Patients received toripalimab 240 mg every 3 weeks for up to 16 cycles.

RADIATION

Intensity-modulated radiotherapy

All patients received external-beam radiation using intensity-modulated radiotherapy. The prescribed dose is 54 Gy in 27 fractions over 5-6 weeks.

Trial Locations (1)

510060

RECRUITING

Mian Xi, Guangzhou

All Listed Sponsors
collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

Zhujiang Hospital

OTHER

collaborator

Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Xiangya Hospital of Central South University

OTHER

collaborator

Wuhan University

OTHER

lead

Sun Yat-sen University

OTHER