A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

July 26, 2023

Primary Completion Date

December 31, 2025

Study Completion Date

June 30, 2033

Conditions
Hemophilia A
Interventions
GENETIC

ANB-010, dose 1

Adeno-associated viral vector carrying the FVIII gene single infusion at dose 1.

GENETIC

ANB-010, dose 2

Adeno-associated viral vector carrying the FVIII gene single infusion at dose 2.

GENETIC

ANB-010, dose 3

Adeno-associated viral vector carrying the FVIII gene single infusion at dose 3.

Trial Locations (17)

125167

"Federal State Budgetary Institution National Medical Research Centre for Hematology of the Ministry of Health of Russian Federation (Department of Clinical Diagnostics for Hematology and Hemostasis Disorders)", Moscow

"Federal State Budgetary Institution National Medical Research Centre for Hematology of the Ministry of Health of Russian Federation (Department of Traumatology and Reconstructive and Restorative Orthopedics for Patients with Hemophilia)", Moscow

Research Center for Hematology MHSD RF, Moscow

125284

"Federal Budgetary Institution Moscow City Clinical Hospital named after S. P. Botkin", Moscow

167904

"State Institution Komi Republican Oncological Dispensary", Syktyvkar

188300

State budgetary healthcare institution Leningrad Regional Clinical Hospital, Gatchina

191024

Russian Research Institute of Hematology and Transfusiology Federal State Institution of Federal Medical and Biological Agency, Saint Petersburg

191186

City Polyclinic №37, Saint Petersburg

197341

Almazov National Medical Research Centre, Saint Petersburg

443099

"Federal State Budgetary Educational Institution of Higher Education Samara State Medical University of the Ministry of Healthcare of the Russian Federation", Samara

450008

"Federal State Budgetary Educational Institution of Higher Education Bashkir State Medical University of the Ministry of Healthcare of the Russian Federation", Ufa

454048

"State Autonomous Institution for Healthcare Chelyabinsk Regional Clinical Hospital", Chelyabinsk

603137

"LLC Medis", Nizhny Novgorod

610027

"Federal State Budgetary Organization of Science Kirov Research Institute of Hematology and Blood Transfusions of Federal Medical Biological agency", Kirov

620102

"State Autonomous Institution for Healthcare of Sverdlovsk region Sverdlovsk Regional Clinical Hospital №1", Yekaterinburg

630087

State Novosibirsk Regional Clinical Hospital, Novosibirsk

650066

Kuzbass Clinical Hospital named after S.V. Belyaev, Kemerovo

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Biocad

INDUSTRY

NCT06185335 - A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A | Biotech Hunter | Biotech Hunter