Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia

NAActive, not recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

December 12, 2023

Primary Completion Date

September 30, 2025

Study Completion Date

December 31, 2025

Conditions
Aphasia, AcquiredAphasiaAphasia, FluentAphasia Non Fluent
Interventions
BEHAVIORAL

Low-intensity physical exercise

As an active control intervention, a low-intensity non-aerobic exercise program was selected that mirrors more closely the standard-of-care physical therapy currently provided to stroke patients. This control intervention will offer the same level of participant involvement and type of exercises, but without the intensity element, i.e., it will not incorporate the cardiovascular and the strengthening components.

BEHAVIORAL

High-intensity physical exercise

We have developed a new exercise program specifically designed for individuals with post-stroke aphasia, Aphasia Physical EXercise (APEX), to provide a safe, stroke- and aphasia-friendly physical exercise intervention to achieve optimal physical fitness and cognitive/language gains. This intervention, based on published research and clinical practice recommendations, is a high-intensity interval training full-body workout optimized to accommodate the range of motor abilities and general deconditioning observed in stroke survivors.

Trial Locations (4)

94118

University of San Francisco, San Francisco

94143

University of California San Francisco, San Francisco

94542

California State University East Bay, Hayward

94720

University of California Berkeley, Berkeley

All Listed Sponsors
collaborator

University of California, San Francisco

OTHER

collaborator

University of San Francisco

OTHER

collaborator

California State University, East Bay

OTHER

lead

University of California, Berkeley

OTHER

NCT06185023 - Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia | Biotech Hunter | Biotech Hunter