Apixaban for the Prevention of Latent Biological Valve Thrombosis

Patients undergoing first-time isolated aortic valve replacement with a rapid deployment biological prosthesis.

All the study patients will undergo a computed tomography imaging to assess for hypo-attenuated leaflet thickening and reduced leaflet mobility of the biological prosthesis following the three-month treatment period.

All the study patients will undergo a transthoracic echocardiography before hospital discharge and following the three-month treatment period.