Phase I Study of KY-0118 in Subjects With Locally Advanced or Metastatic Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

189

Participants

Timeline

Start Date

December 28, 2022

Primary Completion Date

December 28, 2025

Study Completion Date

December 28, 2025

Conditions
NeoplasmsNeoplasms by Histologic Type
Interventions
DRUG

KY-0118

KY-0118 is to be injected intravenously with a dose of 0.3μg/kg, 1μg/kg, 3μg/kg, 6μg/kg, 12μg/kg, 24μg/kg, 36μg/kg, 48μg/kg or 64μg/kg until disease progresses or unacceptable tolerability occurs;

DRUG

KY-0118

KY-0118 is to be injected intravenously with a dose of dose1\~dose5 weekly until disease progresses or unacceptable tolerability occurs;

DRUG

KY-0118

KY-0118 is to be injected subcutaneously with a dose of dose1\~dose5 weekly until disease progresses or unacceptable tolerability occurs;

Trial Locations (8)

100853

RECRUITING

The Fifth Medical Center of the Chinese PLA General Hospital, Beijing

233030

RECRUITING

The First Affiliated Hospital Bengbu Medical College, Bengbu

252000

RECRUITING

The Second People's Hospital of Liaocheng, Liaocheng

276600

RECRUITING

Qilu Hospital of Shandong University, Jinan

300060

RECRUITING

Tianjin Cancer Hospital, Tianjin

350014

RECRUITING

Fujian Cancer Hospital, Fuzhou

430079

RECRUITING

Hubei Province Tumor Hospital, Wuhan

Unknown

NOT_YET_RECRUITING

Zhejiang Province Tumor Hospital, Hangzhou

All Listed Sponsors
lead

Novatim Immune Therapeutics (Zhejiang) Co., Ltd.

INDUSTRY

NCT06175780 - Phase I Study of KY-0118 in Subjects With Locally Advanced or Metastatic Solid Tumors | Biotech Hunter | Biotech Hunter