19
Participants
Start Date
January 31, 2024
Primary Completion Date
August 4, 2025
Study Completion Date
August 4, 2025
Oral Nutrition Supplement
8oz (240mL) per dose at least once a day, but up to six times per day depending on estimated nutrient needs. The formula will equate to 1.0kcal/mL
Tube Feed
EN will have a feeding tube placed and started on tube feeds via a designated pump for overnight feeds, meeting at least 50% of estimated energy needs
Cyproheptadine
0.25mg/kg/d divided BID. May titrate by 4mg increments to a max of 12mg/day.
Olanzapine
2.5mg once a day (at night). May titrate by 2.5mg increments to max of 10mg/day
Standard of Care
Diet education on high protein, high calorie food consumption
University of Kentucky, Lexington
National Center for Advancing Translational Sciences (NCATS)
NIH
Corey Hawes
OTHER