A Study of Fruquintinib in Combination With Irinotecan and Capecitabine for the Second-line Treatment of Patients

RecruitingOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

June 1, 2023

Primary Completion Date

April 30, 2025

Study Completion Date

June 30, 2025

Conditions
FruquintinibIrinotecanCapecitabineGastrointestinal Tumours
Interventions
DEVICE

fruquintinib

4 mg orally once daily, D1-14, repeated every 3 weeks.

DRUG

Irinotecan

180 mg/m2, IV, day 1, repeated every 3 weeks. (Note: If patient has UGT1A1\*28 and \*6 as pure or double heterozygous variants, irinotecan dose 150 mg/m2, IV, day 1, repeated every 3 weeks, with close clinical observation).

DRUG

Capecitabine

1000 mg/m2 orally twice daily, D1-14, repeated every 3 weeks.

Trial Locations (1)

110001

RECRUITING

First Hospital of China Medical University, Shenyang

All Listed Sponsors
lead

China Medical University, China

OTHER