Transauricular Vagus Nerve Stimulation in Children

NAEnrolling by invitationINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

November 15, 2023

Primary Completion Date

November 15, 2025

Study Completion Date

November 15, 2025

Conditions
Hypoxia-Ischemia, Brain
Interventions
DEVICE

taVNS

Recently, implantable VNS received FDA approval for augmenting motor recovery from ischemic stroke-induced hemiplegia when used during standard physical and occupational therapy sessions. VNS is FDA-approved for epilepsy therapy in children and is used for generalized refractory epilepsy. VNS may be achieved through an implantable stimulator on the left vagus nerve in the carotid sheath, or transcutaneously through the auricular branch of the vagus nerve (taVNS). All participants will be fitted with the device by attaching adhesive contacts to the left ear. Stimulation sessions will occur once for 30 minutes. The investigators will obtain baseline measure, tolerability questionnaires, vital signs, and EEG data.

Trial Locations (1)

63110

Washington University in St. Louis, St Louis

All Listed Sponsors
lead

Washington University School of Medicine

OTHER