TITAN Trial: Reducing Phantom Limb Pain in People with Amputations

NARecruitingINTERVENTIONAL
Enrollment

208

Participants

Timeline

Start Date

December 18, 2023

Primary Completion Date

December 18, 2026

Study Completion Date

December 18, 2027

Conditions
Phantom Limb PainAmputation
Interventions
OTHER

Progressive rehabilitation program

Twelve-week treatment program delivered via eight, up to 1-hour telehealth sessions. The first five sessions will be scheduled every week, and the final three sessions will be scheduled fortnightly. Participants will also be prescribed approximately 15-30 minutes of home activities daily. The treatment program includes pain science education, sensory training, implicit and explicit motor imagery, and mirror therapy. Participants will complete activities at a self-directed pace following a standard progression protocol. Participant adherence will be measured via session attendance and self-report therapy diaries.

OTHER

Stimulation devices

Twelve-week treatment program delivered via eight, up to 1-hour telehealth sessions. The first five sessions will be scheduled every week, and the final three sessions will be scheduled fortnightly. Participants will also be prescribed approximately 15-30 minutes of home activities daily. The treatment program includes transcutaneous electrical nerve stimulation and cranial electrical stimulation. Participants will complete activities at a self-directed pace following a standard progression protocol. Participant adherence will be measured via session attendance and self-report therapy diaries.

Trial Locations (1)

2031

RECRUITING

Neuroscience Research Australia, Randwick

All Listed Sponsors
lead

Neuroscience Research Australia

OTHER