Follow-up Study of Autologous Transplantation of P63+ Lung Progenitor Cells for Treatment of Bronchiectasis

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

December 12, 2023

Primary Completion Date

January 31, 2024

Study Completion Date

January 31, 2024

Conditions
Bronchiectasis
Interventions
OTHER

RNA sequencing is performed on the remaining LPCs

RNA sequencing is performed on the remaining LPCs previously transplanted back into the patients. And the results are analysed combined with the data from the previous clinical trial. (Please note that patients will not receive cell transplantation again as they have already received the treatment in the previous trial \[NCT03655808\])

OTHER

Immunofluorescence staining is performed in the surgically resected lung tissue sections

The aim of this intervention is to detect Krt5 protein expression by staining the surgically resected lung tissue sections. This is done to confirm the presence of a small number of LPCs in the lung tissue of patients with bronchiectasis and to investigate their distribution.

Trial Locations (1)

200025

Ruijin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai

All Listed Sponsors
collaborator

Regend Therapeutics

INDUSTRY

lead

Ruijin Hospital

OTHER

NCT06164093 - Follow-up Study of Autologous Transplantation of P63+ Lung Progenitor Cells for Treatment of Bronchiectasis | Biotech Hunter | Biotech Hunter