Neutrophil Oxidative Burst in Early and Late Onset Pediatric Inflammatory Bowel Disease

RecruitingOBSERVATIONAL
Enrollment

150

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

February 28, 2025

Conditions
Chronic Granulomatous Disease
Interventions
DIAGNOSTIC_TEST

Phagoburst

The main objective is to perform oxidative burst activity in pediatric patients with a definitive diagnosis of IBD and compare them with healthy controls.

DIAGNOSTIC_TEST

Lymphocytes subsets

To determine lymphocytes subsets in patients with suspicion of IEI

DIAGNOSTIC_TEST

Genetic testing

Perform targeted genetic testing in those with reduced to absent oxidative activity in search of PIDs and susceptibility variants

Trial Locations (1)

041249

RECRUITING

National Institute for Mother and Child Health Alessandrescu Rusescu, Bucharest

All Listed Sponsors
collaborator

Marie Curie Emergency Children's Hospital, Bucharest

UNKNOWN

collaborator

Victor Gomoiu Children's Hospital, Bucharest

UNKNOWN

lead

National Institute for Mother and Child Health Alessandrescu Rusescu

OTHER